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Prognostically, higher TFRC/CD71 expression, and consequently increased ferroptosis sensitivity, is correlated with better clinical outcomes, reinforcing the link between iron metabolism and CLL prognosis

EIF2A, a classical downstream target of EIF2AK4, appears to be critical to the mitigation of colitis, as a mouse model of colitis lacking phosphorylated EIF2A (p-EIF2A) in IECs is found to exhibit worsened colitis [49]

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P743: the pivotal role of glutaminolysis in myelodysplastic syndrome (mds): a novel strategy for the targeted therapy of mds

L., Day, N

Okuno M, Adachi S, Kozawa O, Shimizu M, Yasuda I